Gonocytes Assignment: Cell Profile Report

Task: Write a Cell Profile Report (Introduction and Discussion)on Gonocytes which are found in male testis developed from Germ Cells. The key points are provided which are to be followed when writing each section and starting references been provided. I have also attached a sample cell profile report on different cell type. The marking rubric for the assignment is also attached. Further detailed instructions are provided below: Introduction: Cell type – Gonocytes ( brief slides about what is gonocytes is attached in a pdf). This section should be around 3 pages long including images. Provide an introductory paragraph summarising about Gonocytes. What is the function of Gonocytes? Is the function different in the embryo and adult? 3) Where are Gonocytes located? Choose region in which Gonocytes are found and focus on that and mention where else it is found in the embryo? 4) What processes does it go through during embryogenesis (and later) to become the final, functional Gonocyte ? Outline how Gonocytes are developed fertilisation onwards? (eg: Process of how germ cells are developed w/n testis) 5) With what other tissues must Gonocytes interact in order to function? Keep in mind not only proximal tissues, but also important distal interactions eg hormones produced by various glands. (example: Signalling – FGF-2/notch signalling in seminiferous epithelium; LH- aid for apoptosis; FSH- produce ABH by Sertoli cells.) 6) Outline aspects of cell-cell adhesion, proliferation, apoptosis and/or migration important for the development of this cell type (example: Sertoli cells, Leydig cells, Apoptosis- maintain ratio of Sertoli cells; SSC undergo proliferation.) 7) Provide some introductory information to your Discussion topic.( example: Cryptorchidism Definition, % affected, 1-2 lines relate to infertility and how male reproductive health needs attention.) Topic – Cyptorchidism This section should be around 3 pages long, and have a focus on the developmental biology of Gonocytes including images. Few key points of how what should the discussion consist of: (can add in more). How Cyptorchidism relates to Gonocytes/primordial germ cells at least half a page Comparison b/w normal & UD testis; Mention in brief about Diseases(cancer), health conditions(diabetes) disorders (ADHD, ASD) can cause. No presence of BAXprotein, gonadotrophins (LH, TSH) – due to low sperm count not allow apoptosis/ self-renewal/high temperature in testis of Gonocytes. Importance of Mini-puberty Mention of surgery – orchiopexy in children to fix testicles Impact on infertility – comparing % Fertility rates between countries; Discuss the health conditions mentioned at above; how society ignores male reproduction.

Subject Name: Biology

Level: Undergraduate

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